Research dissemination center involves the planning and implementation of the research protocols and communicating the research findings with wider audiences in way, that will facilitate research. It also conducting the
workshops and training for the various topics.
- Good Clinical Practice
- Ethical principles and Helsinki Guidelines
- Data management and Monitoring
- Bio-Statistics and Bio-Informatics
- Research Methodology.
Ongoing & Completed research
| 1 |
Knowledge attitude and practice of breast cancer screening among women in northern Kerala: |
| 2 |
Epidemiologic profile of diabetes among newly diagnosed cancer patients in a tertiary care setting |
| 3 |
Clinical Trail Phase III: Indication: low tumour burden follicular lymphoma |
| 4 |
Immunophenotypic profile of acute leukemia in a tertiary care centre in south India |
| 5 |
Assessment of tumor response and hormonal status in carcinoma breast post neoadjuvant therapy |
| 6 |
Deep learning technique for predecting organs at risk dose distribution of treatment plans in brain tumour patients |
| 7 |
Total neo-adjuvant treatment for high risk rectal adenocarcinoma |
| 8 |
Teravolt study |
| 9 |
Covacare- Development of Remote Patient Monitoring System : Use of Artificial Intelligence Technology |
| 10 |
Development of multiple linear regression model for parotid mean dose prediction in treatment planning |
| 11 |
IMCOC study-the impact of the COVID-19 pandemic on patients with cancer and the consequences for their treatment will be investigated. |
| 12 |
Kerala Triple Negative Breast Cancer Study |
| 13 |
A prospective study of clinical and microbiological characteristics of febrile neutropenia in solid and hematological malignancies |
| 14 |
Quality of life & lived experience of women after radical mastectomy- A study to assess the quality of life( QOL) & lived experience of women after radical mastectomy. |
| 15 |
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) – a single centre ICU experience |
| 16 |
Development of multi-channel brachytherapy applicator |
| 17 |
A prospective study to assess the incidence of biopsy tract seeding in patients with osteosarcoma and Ewing’s sarcoma of the extremity |
| 18 |
Genomic profiling of high grade serous ovarian carcinoma to predict platinum sensitivity: pilot study |
| 19 |
Prognostic significance of Nutrition Risk Index in patients with carcinoma stomach and GE junction |
| 20 |
Total parietal peritonectomy at interval cytoreductive surgery with/without HIPEC for advanced (Stage III-C/IV-A) ovarian, fallopian tube and primary peritoneal cancer- A prospective comparative multi-institutional
study
|
| 21 |
ERAS Practices- working Guidelines and compliance check list |
| 22 |
Patient preference for non-operative treatment strategy in locally Advanced Rectal Cancers; a cross-sectional survey
|
| 23 |
Genome sequencing of multi drug resistant clinical isolates for antimicrobial resistance surveillance |
| 24 |
Clinicopathological profile of epithelial ovarian tumors in a tertiary cancer care centre in south india – a descriptive study. |
| 25 |
Automated tissue necrosis segmentation tool using h&e stained histopathological images |
| 26 |
Genetic profiling of carcinoma endometrium and prognostic significance of mutations in pole gene |
| 27 |
Patient preference for non-operative treatment strategy in locality advanced rectal cancers : a cross sectional survey |
| 28 |
An exploratory study on pain perception among cancer patients |
| 29 |
Indian covid-19 childhood cancer registry
|
| 30 |
Clinical course, pathological spectrum and outcomes in paediatric rare tumors in india: a prospective observational study |
| 31 |
Resilience of care givers of pediatric cancer patients in kerala |
| 32 |
Assessment of nutritional status at diagnosis and over a 6 -months treatment period in paediatric oncology patients haematology malignancies and solid tumours. |
| 33 |
India co-operative neuroblastoma study :non –high risk (icons –nhr18) study |
| 34 |
Glucorticoid induces bradycarisa in children undergoing induction chemotherapy in acute lymphoblastic leukemia |
| 35 |
The impact on covid-19 pandemic on the care of children with cancer in india |
| 36 |
Patterns of care and survival of wilms tumor in india – a retrospective multi-centric study |
| 37 |
A Prospective Collaborative Study for Newly Diagnosed Patients with Retinoblastoma in India (InPOG – RB – 19 – 01) |
| 38 |
Clinical audit of interval compressed VAC/IE schedule in children receiving chemotherapy for Ewing’s Sarcoma |
| 39 |
Comparison of different nutritional assessments in detecting malnutrition in post gastrectomy patients |
| 40 |
Prognostic significance of nutrition risk index in patients with carcinoma stomach and GE junction |
| 41 |
Assessment of Nutritional status at Diagnosis and over a 6 -months treatment period in pediatric oncology patients Hematology malignancies and solid Tumors.- |
| 42 |
Analysis of biological variation, interfering substances and quality management in clinical biochemistry lab - |
| 43 |
Assessment of depth of invasion in anterior two third of tongue with magnetic resonance imaging and correlation with pathological depth of invasion |
| 44 |
Evaluation of sensory changes in neck after selective neck dissection for primary oral cavity cancers |
| 45 |
Deep contour: a u-net based auto-contouring tool for delineration in head and neck based computed Tomography Images |
| 46 |
Clinicopathological characteristics of differentiated thyroid cancer |
| 47 |
Impact of radiation therapy on oral health quality in oral cancer patients |
| 48 |
Knowledge attitude and practice of breast cancer screening among women in Northern Kerala |
| 49 |
Factors affecting blood component expiry in a blood centre attached to an Oncology |
| 50 |
Covid vaccination coverage among health care workers in a tertiary cancer |
| 51 |
Covid test positivity rate and its clinical relevance among cancer patients in a tertiary cancer care center |
| 52 |
Genome sequencing of Multi Drug Resistant clinical isolates for antimicrobial resistance surveillance |
| 53 |
Microwave ablation of hepatocellular carcinoma: Outcomes and prognostic factors. |
| 54 |
Radiogenomic role with respect to MRI techniques, 1p19q status and WHO grade II/III gliomas |
| 55 |
ARGOS Research Project: A study protocol for a federated multi-centre deep-learning neural network collaborative research project on lung cancer Gross Tumour Volume auto segmentation following the
Personal Health Train method |
| 56 |
Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma Patients of Indian Ethnicity |
List Of Publications
1. Ranjith C.P., Puzhakkal, N., Arunkrishnan, M. P., Vysakh, R., Irfad, M. P., Vijayagopal, K. S., & Jayashanker, S. (2021). Mean parotid dose prediction model using machine learning regression method for intensity-modulated
radiotherapy in head and neck cancer. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 46(3), 283–288. https://doi.org/10.1016/j.meddos.2021.02.003.
2. Francis, S., Jayaraj, P.B., Pournami, P.N. Manu Thomas, Ajay Thoomkuzhy Jose, Allen John Binu & Niyas Puzhakkal. ThoraxNet: a 3D U-Net based two-stage framework for OAR segmentation on thoracic CT images. Phys Eng Sci
Med (2022). https://doi.org/10.1007/s13246-022-01101-x.
3. Krishnan, M., Bhagyalakshmi, A. T., Holla, R., Puzakkal, N., Ranjith, C. P., Vysakh, R., Irfad, M. P., Ramasubramanian, V., Hu, J., & Momeen, M. U. (2021). A technique for quantifying the sensitivity of dosimetric tool
gamma with 2D detector array in pretreatment IMRT plans by segment deletion method. La Radiologia medica, 126(3), 453–459. https://doi.org/10.1007/s11547-020-01259-y.
4. R Vysakh, MM Musthafa, CV Midhun, P. Niyas, P T Anjana, MP Arun Krishnan, CP Ranjith, MP Irfad & R Ganapathi Ramanet. (2020). Experimental determination of thermal neutron fluence around Elekta Versa HD linear accelerator
for various photon energies. Biomed. Phys. Eng. Express 6 055018. https://doi.org/10.1088/2057-1976/abac90.
5. Niyas Puzhakkal, Abdullah KK, Dinesh Makuny, Arun Krishnan M.P, Ranjith C. Poyil, Vysakh R,.(2019). Validation of Dolphin dosimetry in three dimensional patient-specific quality assurance programme. Reports of Practical
Oncology & Radiotherapy 24(5), 481-490. https://doi.org/10.1016/j.rpor.2019.07.006.
6. Niyas, Puzhakkal., Abdullah, K., Noufal, M., & Vysakh, R. (2019). Quality assurance of linear accelerator:A comprehensive system using electronic portal imaging device. Journal of Radiotherapy in Practice, 18(2), 138-149.
https://doi.org/10.1017/S146039691800050X.
7. Niyas Puzhakkal, Ranjith, C.P., Arun, M.P., Vysakh, R., Abdullah, K.K., & Noufal, M.P. (2018). Evaluation of structural shielding adequacy of a medical linear accelerator. (2018) India: Raja Ramanna Centre for Advanced
Technology. http://inis.iaea.org/search/search.aspx?orig_q=RN:49082890.
8. Bene A. Ekine-Afolabi, 1 , 2 , * Anoka A. Njan, Solomon O. Rotimi, Anu R. I., Attia M. Elbehi, , Elizabeth Cash, and Ademola Adeyeye, The Impact of Diet on the Involvement of Non-Coding RNAs, Extracellular Vesicles,
and Gut Microbiome-Virome in Colorectal Cancer Initiation and Progression, Front Oncol. 2020; 10: 583372. Published online 2020 Dec 14. doi: 10.3389/fonc.2020.583372
9. Sudeep Guptha, Shona Nag, Shyam Aggarwal, Amit Rauthan, and Narayanankutty Warrier Maintenance therapy for recurrent epithelial ovarian cancer: current therapies and future perspectives – a review, J Ovarian Res. 2019;
12: 103.Published online 2019 Nov 4. doi: 10.1186/s13048-019-0579-0
10. Narayanankutty Warrier, Uma V Sankar, Sreedharan P S, Nirmal V, Sajeevan K V, Ajmal Sherif, Detect Early Be Safe–Care for Mother (DEBS-CaM) project: School-based interventions to improve awareness and screening for
breast cancer among the young mothers of Kerala. 10.1200/JCO.2020.38.15_suppl.e13570 Journal of Clinical Oncology 38, no. 15_suppl
11. Bhatt, A., Sinukumar, S., Rajan, F., Damodaran, D., Ray, M., Zaveri, S., Kammar, P., & Mehta, S. (2019). Impact of Radicality Versus Timing of Surgery in Patients with Advanced Ovarian Cancer (Stage III C) Undergoing
CRS and HIPEC-a Retrospective Study by INDEPSO. Indian journal of surgical oncology, 10(Suppl 1), 57–64. https://doi.org/10.1007/s13193-019-00875-z
12. Damodaran D, Naidu BK, Varghese JC, et al. A Prospective Study on Level of Concordance Between Core Needle Biopsy and Surgical Specimen for Assessing Oestrogen Receptor, Progesterone Receptor, and Her2/Neu Receptor
Status in Carcinoma Breast and Its Implications on Treatment Decisions. Indian J Surg Oncol. 2020;11(3):446-450. doi:10.1007/s13193-020-01146-y
13. Bhatt, A., Kammar, P., Mehta, S., Damodaran, D., Zaveri, S., Patel, M. D., Sinukumar, S., Ray, M., & Seshadri, R. (2019). Chasing Rainbows? the Possibility of "Cure" in Patients with Colorectal Peritoneal Metastases
Undergoing Cytoreductive Surgery and HIPEC-a Retrospective Study by INDEPSO. Indian journal of surgical oncology, 10(Suppl 1), 49–56. https://doi.org/10.1007/s13193-019-00879-9
14. Patel, M. D., Damodaran, D., Rangole, A., Shaikh, S., Shah, K., Bagwade, R., & Bhatt, A. (2019). Hyperthermic Intrathoracic Chemotherapy (HITHOC) for Pleural Malignancies-Experience from Indian Centers. Indian journal
of surgical oncology, 10(Suppl 1), 91–98. https://doi.org/10.1007/s13193-018-0859-y
15. Afra TP, Nair PP, Thanseer NTK, Razmi TM. Crizotinib-Induced Severe Photosensitive Dermatitis in a Carcinoma Lung Patient. Indian Dermatol Online J. 2020;12(1):188-189. Published 2020 Sep 28. doi:10.4103/idoj.IDOJ_291_20
16. Periasamy K, Karunanithi G, Cholayil S, Dharanipragada K, Neelakanadan V. Dosimetric comparison between interstitial brachytherapy and volumetric-modulated arc therapy for tumor bed boost in breast cancer. J Contemp
Brachytherapy. 2021;13(3):302-309. doi:10.5114/jcb.2021.106141
17. Narayanankutty Edavalath Warrier, Uma V Sankar, Sreedharan P. S., Prasanth V. Parameswaran, Sajeevan K. V., Nirmal V. Can COV Direct: Effectiveness of a tele-medicine self- care interventions for cancer survivors during
COVID 19 pandemic.J Clin Oncol 39, 2021 (suppl 15; abstr 1583). DOI. 10.1200/JCO.2021.39.15_suppl.1583
18. Radhakrishnan C, Sankar UV, Rajendran VR, et al. Psychosocial impacts of quarantine among survivors of the Nipah virus infection: a qualitative study. Journal of Global Health Reports. 2021;5:e2021092. doi:10.29392/001c.28993
19. Yamini Krishnan, Gazel Sainulabdin, V. Sankar Uma, P.S. Sreedharan, Narayanankutty Warrier. Clinical audit of a Paediatric Emergency Warning Score (PEWS) in the paediatric oncology unit of a newly established tertiary
cancer institute, Pediatric Hematology Oncology Journal,Volume 5, Issue 3,2020,Pages 69-74,ISSN 2468-1245, https://doi.org/10.1016/j.phoj.2020.06.006.
20. Warrier, Narayanankutty Edavalath, Uma V. Sankar, Sreedharan P S, and Ajmal Sherif. "Triple-negative and non–triple-negative breast cancer in a south Indian cohort." Journal of Clinical Oncology 38, 15_suppl (May 2020):
e13110-e13110. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e13110.
21. Krishnan, Y., Gazel, S., Sankar, U. V., & Sreedharan, P. S. (2021). Glucocorticosteroid Induced Bradycardia in Children Receiving Induction Chemotherapy for Acute Lymphoblastic Leukaemia-an Unrecognised Phenomenon.
Asian Oncology Research Journal, 4(1), 14-23.Retrieved from.https://www.journalaorj.com/index.php/AORJ/article/view/30129
22. Anu R I, Aastha Vatsyayan, Ambily Sivadas, Dileep Damodaran, Kurt Van der Speeten. Multi-omic analysis classifies colorectal cancer into distinct angiogenic and immunogenic subtypes based on anatomical laterality. Cancer
Research. 2022. Abstract published by AACR.
23. Anu R I et al. Mutational Signatures, Variant Topography, and Signaling Pathways in Breast Cancer: A futuristic approach to personalized care. Translational Genomics. 2020. doi:10.9777/tg.2020.10001
24. Anu R I, Gauri Mittal, Aastha Vatsyayan, Kavita Pandhare, Vinod Scaria. MUSTARD—a comprehensive resource of mutation-specific therapies in cancer, Database, Volume 2021,https://doi.org/10.1093/database/baab0423.
25. Cash, E., Sephton, S., Woolley, C., Elbehi AM, Anu R I, Ekine-Afolabi B, Victor Kok. The role of the circadian clock in cancer hallmark acquisition and immune-based cancer therapeutics. J Exp Clin Cancer Res 40, 119
(2021). https://doi.org/10.1186/s13046-021-01919-5
26. Elbehi AM, Anu R I, Ekine-Afolabi B, Cash E. Emerging role of immune checkpoint inhibitors and predictive biomarkers in head and neck cancers. OralOncol.2020;109:104977. doi.org/10.1016/j.oraloncology.2020.104977
27. Ekine-Afolabi BA, Njan AA, Rotimi SO, R I Anu, Elbehi AM, Cash E, Adeyeye A. The Impact of Diet on the Involvement of Non-Coding RNAs, Extracellular Vesicles, and Gut Microbiome-Virome in Colorectal Cancer Initiation
and Progression. Front Oncol. 2020 Dec 14;10:583372. doi: 10.3389/fonc.2020.583372.
28. The GUaRDIAN Consortium, Vinod Scaria, Sridhar Sivasubbu. Genomics of Rare Genetic diseases-experinces from India. Human Genomics. 2019;13(53).
29. Anu R I, Kaur C, Bhavsar P, Prasad J. Genotyping of Lipoprotein(a) Gene Variants in Coronary Artery Disease in Indian Population. Indian J Med Biochem 2021; 25 (2):76-82. doi:10.5005/jp-journals-10054-0178
30. Sudheesh Manoharan, Haripriya Chari, Santhoshkumar.N. Distribution of Metastatic Lymph Nodes in Primary Oral Squamous Cell Carcinoma Journal of Head & Neck Physicians and Surgeons ¦ October 2019 ¦ Volume 7 ¦ Supplement
1
31. Krishnan Y, Smitha B ,Cholayil S .Paroxysmal Sympathetic Hyperactivity - An under recognised entity in paediatric brain tumours: Case report and Review of literature Indian J Med Paediatr Oncol 2020;41:254-6
32. Krishnan Y, Smitha B , Sreedharan PS .Consumption Coagulopathy in Paediatric Sol- id Tumours- A retrospective analysis and review of literature Gulf J Oncolog. 2019 Sep ; 31:66-71
33. Yamini K, Gazel S, V. Uma VS, Sreedharan PS, Narayanankutty W. Clinical audit of a Paediatric Emergency Warning Score (PEWS) in the paediatric oncology unit of a newly established tertiary cancer institute. Pediatric
Hematology Oncology Journal. 2020 Sep ; 5 (3) : 69-74
34. Krishnan, Y., Gazel, S., Sankar, U. V., & Sreedharan, P. S. (2021). Glucocorticos- teroid Induced Bradycardia in Children Receiving Induction Chemotherapy for Acute Lymphoblastic Leukaemia-an Unrecognised Phenomenon.
Asian Oncology Research Journal. 2021; 4(1), 14-23.
35. Yamini K, Gazel S. Shailaj SK, VP Muralikrishnan .Multiple infectious intracranial aneurysms in a child with acute lymphoblastic leukaemia - a fatal complication in a highly curable disease. Asian Hematology Research
Journal. 2021; 4(2),11-17.
36. Totadri S , Mahajan A, Gupta V , Das A, Meena JP, Singh M , Mohammed S , Ag- garwal P, Tuladhar S, Seth R, Naseem S, Varma N, Trehan A, Bansal D -Treatment and outcome of chronic myeloid leukemia in children and adolescents
: The Indian Pediatric Oncology Group - CML-16-01 Multicentric Study. Poster presented at The 24th European Hematology Association Congress (EHA) 2019 ; June 13 -16, Ams- terdam
37. Sharma J, Mahajan A, Bakhshi S, Patil V, Verma N, Radhakrishnan V, Singh A, Kayal S, Seth R, Pushpam D, Arora RS. The impact of COVID-19 pandemic on access to treatment for children with cancer in India and treating
center practices. Cancer. 2021 Oct 7. doi: 10.1002/cncr.33945. Epub ahead of print..
Oral presentation
1. Vishnu K S ,Dileep Damodaran. Enhanced Recovery after surgery (ERAS) in patients undergoing cytoreductive surgery (CRS)& Hyperthermic Intraperitoneal Chemotherapy (HIPEC) – Complaince and Outcome experience at a tertiary
care centre. MIDCON IASO 2022
2. Uma V Sankar, Yamini Krishnan, Rakhi T S, Roshnawilson, Gazel S, Public awareness about Childhood Cancer".14th SIOP Asia Conference, China
Poster Presentations
- Anu RI, Dileep Damodaran, MultiOmics analysis classifies colorectal cancer into distinct angiogenic and immunogenic subtypes based on anatomical laterality, American Association for Cancer research Annual meeting 2022,
New Oreland
- Narayanankutty Edavalath Warrier, Uma V Sankar, Sreedharan P S, Prasanth V Parameswaran, Sajeevan K V, Nirmal V CanCovDirect: Effectiveness of a Tele-Medicine Self-Care Intervention for Cancer Survivors during Covid
19 Pandemic. ASCO annual meeting 2021
- Krishnan Y, Smitha B ,Cholayil S. Paroxysmal Sympathetic Hyperactivity-An under- recognised entity in Paediatric Brain tumours: Case report and Review of literature. Poster presented at International Oncology conference,
MVR Cancer Centre and Re- search Institute, 2018;Sep 28-30; Calicut
- Krishnan Y, Smitha B.Consumption Coagulopathy in Paediatric Solid Tumours- A retrospective analysis from a tertiary referral cancer centre. Poster presented at In- ternational Oncology conference, MVR Cancer Centre
and Research Institute, 2018;Sep 28-30; Calicut
- Sankar U, Krishnan Y, Warrier NK. Paediatric Langerhans cell histiocytosis: single institution experience over 2 years.Poster presented at 2nd International Oncology conference, MVR Cancer Centre and Research Institute,
2019 ; Aug 30-Sep1 ; Cali- cut
- Sankar U, Krishnan Y, Warrier NK. Public perception about childhood cancers: A mixed method study .Poster presented at 2nd International Oncology conference, MVR Cancer Centre and Research Institute, 2019 ; Aug 30-Sep1
; Calicut
- Krishnan Y, Gazel S ,Sankar U, Warrier NK. Clinical Audit of a Paediatric Emer- gency warning score (PEWS) in the paediatric oncology unit of a newly established tertiary cancer institute: Poster at 10 th annual Conference
of Hematology Oncology. Chapter , IAP , Kerala 2019 ; Oct 6 ; Thalassery
- Santhosh kumar N , Krishnan Y, Smitha B, Warrier NK, Manamel M. Fungal suppu- rative Thyroiditis in a child with acute lymphoblastic leukemia. Poster presented at 19th national conference of Foundation for head and
neck oncology FHNO 2019; Oct 11-13 ;Chennai
- Krishnan Y, Sankar U, Gazel S ,Warrier NK. What happens to the parent when their child gets diagnosed with cancer ? A common man’s perspective - a qualitative study. Poster presented at XIIth SIOP Asia Congress 2021,
Mar 19-21; Mumbai
- Sankar U, Krishnan Y, Gazel S ,Warrier NK. Parents perception of childhood cancers in the Malabar Region schools of kerala : A mixed method study. Poster presented at XIIth SIOP Asia Congress 2021, Mar 19-21; Mumbai
- Yamini Krishnan, KrishnanVP, Gazel S, Somdipa Pal, Vyshna Somnath ,Liya Vargh- ese ,Sandhya CT. Factors predicting resilience in parents of paediatric cancer patients in Kerala. Poster presented at 24 th Annual Pediatric
Hematology Oncology Confer- ence 2021, Dec 10-12: Hyderabad
- Somdipa Pal, Yamini Krishnan, Gazel S, KrishnanVP. Extrapleural Pneumonectomy as a surgical management in achild with primary pleural synovial sarcoma-a case report. Poster presented at 24 th Annual Pediatric Hematology
Oncology Conference 2021, Dec 10-12: Hyderabad
- Somdipa Pal, Yamini Krishnan, KrishnanVP, Gazel S. Transitioning of ifosfamide based chemotherapy from the inpatient to an outpatient setting-A cost effective and safe option. Poster presented at 24 th Annual Pediatric
Hematology Oncology Con- ference 2021, Dec 10-12: Hyderabad
Research Collaborations
- Memorandum of understanding (MOU) between National Institute of Technology, Calicut (NIT) for various projects
- MOU with University of Massricht, Netherlands
- MOU with and Arya Vaidya Sala Kottakal (AVS Kottakal) in the project titled ‘Setting up Centre of Excellence in Cancer Research’ to Ministry of AYUSH Government of India
- MOU with Department of Obstetrics, Government Medical College, Calicut
- MOU with CSIR – Institute of Genomics and integrative biology, Delhi in collaborative research
- MOU with KMCT Dental College
- MOU with Malabar Medical College
- MOU with Travencore Analytics
- MOU with Comtrust hospitals
Internship/ trainee opportunities
Department of clinical research offers internship opportunities in clinical trial unit for various streams of students ex: Pharm D Students , B Pharm and Msc Biotech students.
